Prof. Qun Sophia Zang

Prof. Qun Sophia Zang

Important experience / 重要經歷
Associate Professor, Burn & Shock Trauma Research Institute, Department of Surgery, Loyola University Chicago
芝加哥羅耀拉大學外科系燒傷與衝擊型創傷研究所副教授

Research Areas / 研究範疇
Cell Biology
細胞生物學

Immunology
免疫學

Microbiology
微生物學

Pathology
病理學

Physiology
生理學

Biochemistry & Molecular Biology
生物化學與分子生物學

Introduction / 簡介

My research in the past decade has focused on cardiac failure in sepsis, a life- threatening condition of organ dysfunction caused by a deregulated host response to infection. Our goal is to understand the mechanisms underlying sepsis-induced, multi-organ failure, and to identify potential new drug targets for this devastating critical care condition. With continuous funding from NIH, we have been investigating the signaling cascade about how injured mitochondria and related production of mitochondria-derived, danger-associated molecular patterns (DAMPs) incite myocardial inflammation, oxidative stress, and cardiac dysfunction in sepsis using preclinical in vitro and in vivo models.

(節錄自：https://www.luc.edu/stritch/bstri/faculty/profiles/zangqunsophia.shtml)

在過去十年裡，Dr. Zang的研究著重在敗血症引起的心臟衰竭，這是因感染而失衡的宿主反應，造成危及生命的器官功能障礙。Dr. Zang的團隊目標是希望釐清敗血症引起多重器官衰竭的潛在機制，並且找出潛在的藥物來治療這種毀滅性的臨床重症。通過美國國家衛生院持續資助，Dr. Zang團隊使用臨床前的體外和體內模型，研究損傷的粒線體，和其衍生的損傷相關分子模式(DAMPs)引起的心肌炎、氧化壓力，和敗血症引起的心臟衰竭的訊號傳遞。

(節錄並翻譯自：https://www.luc.edu/stritch/bstri/faculty/profiles/zangqunsophia.shtml)

More about the speaker / 更多關於講者
https://www.luc.edu/stritch/microbio/people/faculty/profiles/zangqunsophia.shtml